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Medicine, Discoveries

"Snap chemistry", to discover the Nobel science that will change the world

Everything you need to know to understand why snap chemistry was awarded the Nobel Prize in Chemistry. In one click!

October 6, 2022
Gianluca RiccioGianluca Riccio
⚪ 4 minutes
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Winning a Nobel isn't an everyday thing, but for some it doesn't just happen once. There are only five scientists who are part of this small club, and the last in order of time, Barry Sharpless, he came from Co-parent of "Snap Chemistry".

What is Snap Chemistry

Snap chemistry is a way of joining molecules together as if they were Lego bricks. So, I said it brutally, but if you're still curious I'll go ahead.

Imagine two people meeting, approaching and shaking hands. It is a perfect metaphor for defining a classic chemical reaction.

But what if these two people want to meet and shake hands in a crowd at a stadium during a concert? Things get harder.

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Coming to meet, recognizing each other, finding each other, connecting: with the "click" mechanism, two molecules will be able to do it much more easily, even in a "chaotic" environment.

In one click

As mentioned, the way in which the chemistry of clicks brings together the molecular building blocks is often compared to Lego bricks. For Carolyn Bertozzi, which he shared this year's Nobel Prize in Chemistry with Barry Sharpless e Morten Meldal, you need two very special bricks.

Two bricks capable of hooking together even if they are in different points of a box that contains millions of other pieces.

Nobel Prizes don't come by chance, right? Neither for this one, nor for other sciences. And sometimes they come from afar, as in the case of snap chemistry, which practically took its first steps at the beginning of the century: the year 2000.

The "co-parents" of snap chemistry awarded the Nobel Prize in Chemistry 2022. From left: Bertozzi, Meldal, Sharpless. Those involved in the study of these things would deserve applause regardless, but a Nobel is more welcome, of course :)

All thanks to the copper

2000, I was saying. That year, Sharpless and Meldal discovered (separately, this is also serendipity) a specific chemical reaction produced using copper ions as a catalyst. It was the turning point, the beginning of everything.

Copper has many many qualities, one of them being the ability to include water in chemical reactions and be able to run them at room temperature without having to reach high heat first.

Since then, the discoverers of this reaction have begun to explore. Thing? All the possible types of molecular architecture that can be built these "special bricks" with different chemicals. And they found that the applications are almost endless. Snap chemistry was born.

Problems and solutions

The problem with using copper as a catalyst was that this metal can be toxic to the cells of living organisms, including humans.

For this Carolyn Bertozzi has designed a way to exploit snap chemistry without using copper, and therefore without creating any problems for living organisms.

The dawn of a new era

Many experts wonder if this Nobel (the second, in Sharpless's case) is not a bit premature, given the fact that this young science has not yet found commercial applications.

The truth is, this looks like an award born of full enthusiasm, because the future of snap chemistry looks really, really bright.

This chemistry will change the world

Angela Wilson, President of the American Chemical Society

What Snap Chemistry is for

There are so many potential uses for snap chemistry that making a list is virtually impossible.

He will be able to strive to develop new targeted drugs, who manage to "make their way" into the patient's body to get to their destination in the right place.

Will you give us a more precise way to cancer diagnosis and treatment, with fewer side effects and lighter.

It can make bacteria fluorescent which cause legionella, in order to be able to identify them in water reserves. Indeed, it has already happened. It can produce very, very durable polymers that protect from heat, or glues for nanochemistry.

Snap chemistry will revolutionize everything from medicine to materials. Welcome to the world, and congratulations to your Nobel "parents".



GPT Chat Megaeasy!

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To submit articles, disclose the results of a research or scientific discoveries write to the editorial staff

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