Near future
No Result
View All Result
October 2, 2023
  • Home
  • Tech
  • Health
  • Environment
  • Energy
  • Transports
  • Spazio
  • AI
  • concepts
  • H+
Understand, anticipate, improve the future.
CES2023 / Coronavirus / Russia-Ukraine
Near future
  • Home
  • Tech
  • Health
  • Environment
  • Energy
  • Transports
  • Spazio
  • AI
  • concepts
  • H+

Understand, anticipate, improve the future.

No Result
View All Result
Medicine

Osteocalcin, discovered its role: it is a stress hormone

A study published today reveals the true role of osteocalcin produced by bones: it is a stress hormone, and this subverts current knowledge.

12 September 2019
Gianluca RiccioGianluca Riccio
⚪ 3 minutes
Share37Pin6Tweet18SendShare5ShareShare4

READ IN:

A research published today in the Cell Metabolism journal sheds light on the role of osteocalcin, a substance produced by bones. It is released in response to acute stress: in fact it is therefore a stress hormone.

This path typical of the "fight or flight" mode, typical of different living beings is different and separate from those already known. The latter depend on cortisol, adrenaline and norepinephrine, all produced by the adrenal gland.

The discovery helps understand why people and animals sometimes produce acute stress responses even in the absence of cortisol and other molecules.

osteocalcin

A revolutionary change

"The circumstance that the bones participate in the stress response is totally new. Just like the one that sees the adrenal gland lose the scepter of the only precious one responsible for this response," says the author of the study, Gerard Karsenty of Columbia University Irving Medical Center. "This discovery reinforces the thesis that bones have developed in part as a tool for coping with serious dangers. And clinically it confirms the evidence that we respond better to dangers when young, when our osteocalcin rate is highest." .

The article continues after the related links

RMIT: "We know how to regrow bones using sound waves"

Soon there will be 3D printed bones directly in the human body

The acute stress response, better known as the "fight or flight" response, is mediated by the parasympathetic nervous system (I talked about it about a really interesting device). It plays a crucial role in animals' reaction to sudden danger. The adrenal gland, positioned right next to the kidneys (it can also be seen from the name) releases a series of hormones that produce different physiological responses. Increase in body temperature, breathing, pressure, heart rate and other mechanisms that prepare the muscles for action.

One of the classic puzzles about stress responses is the characteristic of hormones such as cortisol. It takes hours to affect physiological responses, how could it be used to respond to sudden dangers? "Although this discovery does not rule out that hormones glucocorticoids are involved in some capacity related to the stress response, there is the possibility that other hormones are involved, probably the peptide ones, " Karsenty says.

Karsenty and his colleagues suspect that bone-derived hormones contribute to the stress response because the argument matches the history of bone itself.

Structures born to face dangers

Bones protect internal organs from trauma, allow you to trigger more explosive shots and are part of the best listening processes, essential for the prevention of a danger.

Osteocalcin itself is already known for its function of strengthening muscle functions and supporting memory. Two other essential tools to escape from danger and remember a predator.

The laboratory evidence

Lab tests confirmed the research of Karsenty and colleagues: osteocalcin is the only hormone from the bones that increases in case of stress. In mice subjected to acute stress it grew by 150% in 15 minutes, remaining in circulation for up to 3 hours later. In men too, circulating osteocalcin increased significantly in tests, when volunteers were subjected to stress.

The research will now extend to primates to better define the neuronal path from the brain to the bones - the very first response to a danger.

Tags: OssaosteocalcinStress

Latest news

  • Comment la CVP Impack Machine de Sparck Technologies peut Revolutionner l'Industrie de l'Emballage
  • Nobel Prize for Medicine to the creators of the mRNA techniques behind the Covid vaccines
  • SciMatch: take a selfie and meet your soulmate
  • The future glucose monitoring? A new, ingenious sweat sensor
  • From death to passion: if spider venom overcomes erectile dysfunction
  • Getting old? No, thanks: the future of longevity between research and speculation
  • Videogames and photorealism: increasingly thin border between game and reality
  • This is how a war between humans and artificial intelligence would end
  • The alarm of Japanese scientists: microplastics also in the clouds
  • Lawk One AR Glasses: augmented reality for high-tech cyclists


GPT Chat Megaeasy!

Concrete guide for those approaching this artificial intelligence tool, also designed for the school world: many examples of applications, usage indications and ready-to-use instructions for training and interrogating Chat GPT.

To submit articles, disclose the results of a research or scientific discoveries write to the editorial staff

Enter the Telegram channel of Futuroprossimo, click here. Or follow us on Instagram, Facebook, Twitter, Mastodon e LinkedIn.

FacebookTwitterInstagramTelegramLinkedInMastodonPinterestTikTok

The daily tomorrow.


Futuroprossimo.it provides news on the future of technology, science and innovation: if there is something that is about to arrive, here it has already arrived. FuturoProssimo is part of the network ForwardTo, studies and skills for future scenarios.

  • Environment
  • Architecture
  • Artificial intelligence
  • Gadgets
  • concepts
  • Design
  • Medicine
  • Spazio
  • Robotica
  • Work
  • Transports
  • Energy
  • Edition Francaise
  • Deutsche Ausgabe
  • Japanese version
  • English Edition
  • Portuguese Edition
  • Read more
  • Spanish edition

Subscribe to our newsletter

  • The Editor
  • Advertising on FP
  • Privacy Policy

© 2023 Near future - Creative Commons License
This work is distributed under license Creative Commons Attribution 4.0 International.

No Result
View All Result
Understand, anticipate, improve the future.
  • Home
  • Tech
  • Health
  • Environment
  • Energy
  • Transports
  • Spazio
  • AI
  • concepts
  • H+