I often find myself thinking that true genius lies in making the ordinary extraordinary. And what is more ordinary than dental floss? Yet, in the hands of researchers at Tufts University, this humble oral hygiene tool has morphed into a sophisticated medical device. A sensor capable of precisely measuring cortisol levels in your saliva as you brush your teeth. Ironically, the same object you use to remove food debris can now remove the uncertainty of how much stress you are accumulating. It’s like discovering that your coffee maker can also predict the weather: unexpected, but tremendously useful.
How this little prodigy works
The device created by researchers at the Tufts University It is a piece of clever engineering. It is a regular dental floss equipped with a special filament that contains a microfine hair. When you use it, this thread collects saliva and transports it to a tiny electrochemical sensor in the handle.
To create this sensor, researchers developed something called “electropolymerized molecularly imprinted polymer” (eMIP). In layman's terms? They pressed cortisol molecules into a substrate and then removed them, leaving an imprint. When saliva reaches this imprint through the thread, the cortisol molecules present collect in the empty cavities, fitting together like a puzzle and generating a signal that is sent to a mobile device.
The more molecules you collect, the stronger the signal: here's your stress level measured in real time, while you do something that (I hope for you) you do every day anyway.
A monstrously precise dental floss
This is no cheap tech toy. In tests, this floss has been shown to be as effective as one of the gold standards for cortisol testing: the saliva ELISA test. According to researchers, it is one of the best cortisol identifiers ever reported. The analysis takes about 10 minutes, a reasonable amount of time considering you don't have to go to any lab. You basically have a testing lab in your bathroom, built into something you would use anyway. The study, if you want to know more, was published in the journal ACS Applied Materials and Interfaces.

Why Measuring Cortisol Is Important
Cortisol is a stress hormone produced by the adrenal glands. Normal levels are essential for regulating multiple biological functions, but when chronically elevated, they can be linked to a variety of problems: weight gain, insulin resistance, and even a higher risk of developing diabetes.
Chronic stress is one of the most biologically disruptive forces in modern life. It can wake your brain up to 100 times a night, double your risk of developing Alzheimer's, and trigger uncontrolled inflammation. That's why researchers have been hunting for a rapid sensor to measure it (here a study from last September). And now they seem to have finally developed it.
A direct (dental) floss to the future
There are already tests to measure cortisol, of course, but they require you to collect blood or urine samples and send them to a lab. With the smart flosser, you can easily monitor your cortisol levels, and if you notice them rising, you can take steps to reduce them through dietary or lifestyle changes. Researchers believe that in the future, this device could be modified to detect other biomarkers in saliva, making home health testing part of an activity that many (should) already do on a daily basis. Yes, because this smart dental floss could be just the beginning. Experts at American Chemical Society They believe the technology could be adapted to detect other health markers in saliva, turning a daily hygiene gesture into a comprehensive medical check-up.
I don't know about you, but I find it fascinating how science can take something as mundane as dental floss and turn it into a tool to improve our mental health. It shows that innovation doesn't have to be complex to be revolutionary. Sometimes, the best solutions are right in front of us: or in this case, between our teeth.