Near future
Contacts
  • Home
  • Tech
  • Health
  • Environment
  • Architecture
  • energia
  • Transportation
  • Spazio
  • AI
  • concepts
  • Gadgets
  • Italy Next
  • H+
May 24, 2022

Coronavirus / Russia-Ukraine

Near future

News to understand, anticipate, improve the future.

No Result
View All Result

News to understand, anticipate, improve the future.

Read in:  Chinese (Simplified)EnglishFrenchGermanItalianJapanesePortugueseRussianSpanish

CINDELA, created a cancer treatment with no side effects

A joint research team has developed Cindela, a "genetic surgery" method to tackle cancer without side effects

Gianluca Ricciodi Gianluca Riccio
in Medicine
Share228Pin52Tweet143SendShare40ShareShare29
genetic editing russia.630x360

genetic editing side effects

February 25 2022
⚪ Reads in 3 minutes
A A

THEInstitute for Basic Science (IBS) andUlsan National Institute of Science and Technology (UNIST) announced on February 23 the completion of Cindela. It is a therapeutic approach with no side effects. In other words, it can be used on any cancer without causing collateral damage to normal cells.

The results of the study were published in the February 22 edition of the scientific journal Proceedings of the National Academy of Sciences of the United States of America.

The fight against the side effects of oncological treatments

cures cancer without side effects
Kyung Jae Myung, at the helm of the laboratory that has developed new genetic "scissors" for the treatment of cancer without side effects.

Side effects of existing cancer therapies are caused by damage to the DNA double helices. This happens both in normal cells and in tumor cells induced by the latter. Using genetic scissors CRISPR / Cas9, the unique mutant DNA double helices found only in cancer cells can be selectively destroyed by the method developed by the joint research team.

Maybe you are also interested

Vaxinia, first patient receives oncolytic virus that kills cancer

A 'ketogenic' molecule hinders colorectal cancer

A nano-drug precisely attacks chemotherapy-resistant cancer

Scientists are using CRISPR to create hypoallergenic cats

This method based on "genetic surgery" done with CRISPR "traditional scissors" has drawbacks. Mainly, it requires lengthy processes and a lot of work because every carcinogen has to be discovered first, and only then the genetic scissors have to be developed for the necessary "repairs".

Cindela changes the "scissors", and the rules of the game

The South Korean research team used bioinformatics to find mutants of the cancer cell line. Later, he developed the CRISPR Cindela genetic scissors to target the anomalies and tested them on mice. Result? Selective cell killing and tumor cell growth arrest, without side effects.

Researchers have given this new therapy a name: CINDELA. An acronym that translates to “Cancer-specific InDel Attacker”. In short, CINDELA is able to destroy cancer cells without damaging normal ones.

Cancer cell mortality triggered by CINDELA was found to depend on the number of DNA double-strand breaks produced by CRISPR-Cas. For example, the CINDELA reagent which induced 50 breaks in DNA was much more effective in killing cancer cells than the reagent, which induced only 10 breaks.

Subsequent stages

Researchers have already begun to apply this technology against tumors taken directly from patients, with expert research groups in different disciplines (such as gene delivery, the complementary diagnostic platform and cancer genomics). In the near future, the development of new delivery systems will help establish CINDELA cancer treatment technology in cancer patients.

And it will be the end of the side effects.

tags: cancerCRISPR
Previous post

“C-Ecology”, 3D printed ecosystem to revitalize urban rivers

Next Post

A new artificial neuron can fuse with a living plant

COLLABORATE

To submit articles, disclose the results of a research or scientific discoveries write to the editorial staff
  • capacitor

    ETH technology: drinking water from the air 24 hours a day, without power supply

    9829 Shares
    Share 3930 Tweet 2457
  • Domus, crazy zero-emission trimaran

    12605 Shares
    Share 5040 Tweet 3150
  • Winds of war, China launches the Zhu Hai Yun, the world's first "bearer"

    2834 Shares
    Share 1134 Tweet 709
  • Vaxinia, first patient receives oncolytic virus that kills cancer

    2312 Shares
    Share 924 Tweet 577
  • University of Maryland, new study: there would be a reality beyond this

    2051 Shares
    Share 820 Tweet 513

archive

Have a look here:

black hole and big bang
Spazio

Does the Big Bang come from an open black hole in other universes?

BHBBT is the theory that the Big Bang originated from a black hole. Reformulation: part of a ...

Read More

IKEA creates "nomadic" furniture

4253C497 A302 4CDA B4C3 C1C58EA52025

Eliminating a protein could prevent heart attacks and strokes

All about Mi Lux TV, the first transparent TV in the world

Apple focuses on health and buys Gliimpse

Next Post
Artificial neuron

A new artificial neuron can fuse with a living plant

The daily tomorrow

Futuroprossimo.it provides news on the future of technology, science and innovation: if there is something that is about to arrive, here it has already arrived. FuturoProssimo is part of the network ForwardTo, studies and skills for future scenarios.

Subscribe to our newsletter

Environment
Architecture
Artificial intelligence
Gadgets
concepts
Design

Staff
Archives
Advertising
Privacy Policy

Medicine
Spazio
Robotica
Work
Transportation
energia

To contact the FuturoProssimo editorial team, write to redazione@futuroprossimo.it

Chinese Version
Édition Française
Deutsche Ausgabe
Japanese version
English Edition
Edição Portuguesa
Русское издание
Spanish edition

The daily tomorrow

Futuroprossimo.it provides news on the future of technology, science and innovation: if there is something that is about to arrive, here it has already arrived. FuturoProssimo is part of the network ForwardTo, studies and skills for future scenarios.

Chinese Version
Édition Française
Deutsche Ausgabe
Japanese version
English Edition
Edição Portuguesa
Русское издание
Spanish edition

Staff
Archives
Advertising
Privacy Policy

Subscribe to our newsletter

To contact the FuturoProssimo editorial team, write to redazione@futuroprossimo.it

Categories

This work is distributed under license Creative Commons Attribution 4.0 International.
© 2021 Futuroprossimo

No Result
View All Result
  • Home
  • Tech
  • Health
  • Environment
  • Architecture
  • energia
  • Transportation
  • Spazio
  • AI
  • concepts
  • Gadgets
  • Italy Next
  • H+
This site uses cookies. By continuing to read it, you consent to their use.