No Result
View All Result
Sunday, January 17, 2021
Chinese (Simplified)EnglishFrenchGermanItalianJapanesePortugueseRussianSpanish
  • |
  • Tech
  • Medicine
  • Society
  • Environment
  • Spazio
  • Transportation
  • Weather
  • concepts
  • H+
No Result
View All Result

Covid-19 Updates »

9 September 2019
in Medicine

The conservation time of a liver to be transplanted has been tripled

Chinese (Simplified)EnglishFrenchGermanItalianJapanesePortugueseRussianSpanish

Collaborate!

We are open to visions about the future. Submit an article, disclose the results of a search or scientific discoveries, shows points of view on a theme, tells about a change.

CONTACT US
The conservation time of a liver to be transplanted has been tripled
Share82Pin1Tweet4SendShare1
tags: storagecryonicsLiverPerfusiontransplants

A series of methods triples the retention time of a liver to be transplanted. It will save the lives of many patients.

Gianluca Ricciodi Gianluca Riccio
3 minutes of reading

The last

Nectome wants to preserve (and digitize) your brain

Zaha Hadid's Tower C in Shenzen looks like something out of Star Trek

Forestry robots can plant thousands of trees a day

Biden settlement, US survey: 79% of the country is collapsing

Neom, the linear city in Saudi Arabia will be 170km long

Read also:

future world map

Take a look at the future world map

Mobi, smart trolley that acts as a shopping assistant

Mobi, smart trolley that acts as a shopping assistant

personalized shampoo

Gemmist, personalized shampoo is growing in a still immature market

end of the pandemic

How will Covid-19 become at the end of the pandemic?

ArchelisFX, exoskeleton chair for standing

ArchelisFX, exoskeleton chair for standing

mental disorders

Mental disorders at CES2021: iSyncWave, diagnosis and portable therapy

lingkai, swab robot

Covid, China is using the Lingcai robot to make swabs

Milrem presents a fearsome robotic tank

Milrem presents a fearsome robotic tank

Bot Handy, Samsung presents the butler robot at CES2021

Bot Handy, Samsung presents the butler robot at CES2021

measure blood sugar without needles

CES2021, here is the smartwatch that can measure blood sugar without needles

vaccination center

Disneyland will transform into a giant vaccination center

MRNA vaccines: Covid today, Cancer tomorrow

MRNA vaccines: Covid today, Cancer tomorrow

Read also:

Nectome wants to preserve (and digitize) your brain

Nectome wants to preserve (and digitize) your brain

A team of scientists has vastly extended the time window in which a liver to be transplanted can be kept waiting to reach a patient.

By modifying a protocol necessary to conserve the liver of rodents, the scientists observed results so promising that they were tested on a human liver to be transplanted.

Maybe you are also interested

Plant-based food preservatives are the future of distribution

Regenerate human skin from fish skin

New technique can double the lungs to be transplanted

Brain cell transplantation: in mice it cures damage from multiple sclerosis

The liver of a donor had an average "life" of 9 hours, the new method brings this time to 27 hours. A sea of ​​extra time to organize the operation, to increase the organ's transport range, to prepare the recipient.

A great, great discovery.

The research is supported byUSA National Institute of Bioengineering (NIBIB) and by other entities of the American National Institute of Health.

What happens to a liver to be transplanted

Like a glass that breaks when it gets too cold, cells often receive irreparable damage from the freezing process. The sensitivity of human cells involves the need to freeze a donor's liver below 4 ° C. This brings the useful time to a transplant to 9 hours, beyond which the damages of the cold become irreversible.

This is why it is often very difficult, and sometimes impossible, to get compatible organs to reach people waiting for a transplant.

"Delivering healthy organs in the window of time is one of the most complex aspects of organ transplantation," says Seila Selimovic, Ph.D, director of the NIBIB tissue engineering program. "Giving doctors and patients more time means saving a lot of people waiting for a transplant."

The first research

A study by Massachusetts General Hospital (MGH) in Boston led to a new technique to extend the preservation of rodent liver tissue below zero.

The result was obtained by adding a glucose compound, 3-OMG, and an ingredient, PEG-35kD, to the solution to preserve the tissues, at the base of some antifreeze.

The PEG substance lowers the freezing temperature of the cells and the 3-OMG acts as a protection. This allowed the rat livers to be stored at -6 ° C without freezing them. A process called "super cooling".

Unfortunately, the process did not work with human livers, which being 200 times larger presented more risk of ice crystal formation, rendering the organ useless.

The perfusion process distributes the coolant homogeneously over the liver to be transplanted

The solution of the problem

In the paper published today in Nature Biotechnology, a research team at Harvard Medical School has shown three fixes that solved the problem.

First, limit the contact of the coolant with the air. The team removed oxygen from the container before pouring the liquid, eliminating any risk of crystals on the outer surface of the organ.

Second, two ingredients have been added to the original solution to specifically protect hepatocytes: the trehalose helps protect cells and stabilizes their membranes. The glycerol supports the properties of the glucose contained in the original solution.

Third, a new organ transport method was developed. The previous one involved the manual pouring of the liquid on the organ. The current liquid is more viscous and to pour it they used the perfusion, a method to distribute it in a more uniform and capillary way.

This method will allow organs to travel even over long distances, reaching many more waiting patients.

Comment this post on all the social networks where Futuroprossimo.it is present ( Facebook, Instagram, Twitter, Telegram, Linkedin, Vkontakte, Flipboard )

The future of:

Artificial intelligence

Engineers use AI to convert ancient maps into satellite images

transhumanism

A special hyperbaric therapy can stop and reverse aging

Super Gadgets

CLIP, portable electric motor that turns every bike into an ebike

Design

Therapeutic tools like Balisa help patients see healing

Most read of the week

  • CLIP, portable electric motor that turns every bike into an ebike

    CLIP, portable electric motor that turns every bike into an ebike

    265 shares
    Share 106 Tweet 66
  • Australia, found the way to cure Crohn's disease

    7270 shares
    Share 6123 Tweet 478
  • Pentagon UFO task force ready to reveal its findings

    343 shares
    Share 137 Tweet 86

The last

Woodnest, the hanging houses with breathtaking views of the Norwegian fjord

DARPA at work on night vision goggles as large as normal glasses

Team develops new gene therapy to extend lifespan

Teleportation: is it really impossible? Where are we at?

AR Cloud, the new generation of "virtual life" superimposed on the real one

Next article

Democracy is about to collapse

Futuroprossimo.it is an Italian resource of futurology opened since 2006: every day news about the near future. Scientific discoveries, medical research, prototypes, concepts and predictions about the future for free.

Tag

Environment Architecture Communication concepts Advice Energy Events Gadgets The future of yesterday The newspaper of tomorrow Medicine Military Weather Robotica Society Spazio Technology transhumanism Transportation Video

Categories

The author

Gianluca Riccio, copywriter and journalist - Born in 1975, he is the creative director of an advertising agency, he is affiliated with the Italian Institute for the Future, World Future Society and H +, Network of Italian Transhumanists.

Collaborate! Are you interested in writing a post on Futuroprossimo? Click here for contacts.

Home / Author / IDEA / archive / Promo on FP

© 2020 Futuroprossimo - Tailored by Be Here

© 2020 Futuroprossimo - Tailored by Be Here

  • Home
  • Contact us
  • archive
  • Technology
  • Medicine
  • Transportation
  • Weather
  • Society
  • Environment
  • transhumanism

© 2019 Futuroprossimo - Tailored by To be here

This site uses cookies. By continuing to read it, you consent to their use.